Bess (Lady Cavendish) writes to Sir John Thynne with news of 'disordered things' recently put 'into some good order', including relations with her tenants. She hopes Thynne can visit Chatsworth on his next trip to London or when visiting his estates in Yorkshire.

Mary Percy, widow of Henry, sixth earl of Northumberland, writes to Bess (Lady Cavendish) about land and cattle disputes involving the letter bearer and one of Bess's servants.

Sir George Pierrepont writes to Bess (Lady St. Loe) thanking her and her husband, William St. Loe, for the 'great pains taken with me at Holme'; further thanking Bess for her support in a suit of his; and expressing the desirability of a match between Bess's daughter Frances and his son Henry.

Bess (Lady St. Loe) writes to Henry Babington of Dethick (Derbyshire) concerning lands, postponing a meeting on Babington's holdings until she receives further information regarding the lands' values. Babington forwards the letter (adding a postscript and second superscription) to one Alexander White and gives further instructions to fulfil Bess's requests.

Bess (countess of Shrewsbury) writes to one Henry Foljambe, concerning a recently widowed woman, Elizabeth Flint, who has asked that her brother Roland, currently in Bess's employment, be sent to her for 'urgent cause to employ him otherwise'. Bess asks Foljambe to favour the woman's cause.

Bess (countess of Shrewsbury) writes to Lord Thomas Paget, reprimanding him about persuading her son Henry to negotiate an agreement with unspecified contemptible parties, which has been to Henry's disadvantage. She asks Paget to 'stand the more [Henry's] friend' for the conclusion of the matter.

An unidentified author ('John') writes to advise Bess (countess of Shrewsbury) to look into the legal matter of William Vaughan's outlawry, which will result in confiscation of his lands, and thus possibly Bess's financial disadvantage. Further, he is waiting for Bess's instructions regarding proceedings with one Cole.

A correspondent 'Jo.L.' (perhaps John Lenton) writes somewhat cryptically of a matter concerning Bess (countess of Shrewsbury) and 'Master Pierrepont', himself acting 'as a mean between the two parties, loving both so well as none better'. He has heard that Anne Pierrepont is in love with one Teverle Teyvle, which leaves Bess's 'hope of Master Chaworth that ways daunted'. Master Pierrepont has a book of his called 'Galen in physick', which has assured Pierrepont that 'wedlock helpeth and hurteth not that thing'.

George, sixth earl of Shrewsbury, writes to his wife, Bess (countess of Shrewsbury), regarding the Peak's men's 'clamorous speeches' and a potential meeting with them. On a second page, he writes 'I write this because you may send my letter to them to see how little I account of their complaints'. In a postscript to the latter section, he explains that he will provide 'some place' for his son, Gilbert Talbot and the latter's wife, Mary (née Cavendish; Bess's daughter), but seeks Bess's advice in the matter. He also describes an episode in which Bess's son Charles Cavendish, along with some servants, went stealing out into the country at night, and asks her to advise him against such behaviour.

An unidentified author writes to Bess (countess of Shrewsbury), apologising for a delayed response to her letters due firstly to sickness and then the recent visit of Jean de Simier to the English court. The writer fears that a letter forwarded from 'my cousin Sidney' has not reached Bess and has therefore sent her another copy. Also, Bess's son, 'master Cavendish', has not been seen since her last departure, but the writer would wish him there now in order to introduce him to 'my cousin' for a potential match.

Francis Leake writes to Bess (countess of Shrewsbury) concerning his acquisition of land from the earl of Leicester and related title disputes.

An unidentified author writes to Bess (dowager countess of Shrewsbury), offering her 'better pennyworth of my land than any other shall obtain at my hands', but admitting 'we are not likely to agree for this bargain'. The writer also refers to the execution of a writ for Master Nedham, hoping it will not be hindered by 'this disagreement between your Ladyship and myself'.

Bess (countess of Shrewsbury) writes to Lord Thomas Paget on behalf of 'Master Duport of Bretby', who has been 'molested by some of your lordship's tenants', with 'diverse suits between them'. She asks that Paget intercede in order to restore peace.

A document containing several copies and/or drafts of letters: The first is from an unidentified author to Bess (dowager countess of Shrewsbury) to do with the 'woods about Alton Park as are meet to be dispended in the ironworks there'. Following this are letters from an unidentified writer to Gilbert, sixth earl of Shrewsbury (Bess's stepson and son-in-law), and from an unidentified writer to an unidentified addressee, also on the subject of 'woods'.

Bess (dowager countess of Shrewsbury) writes to Sir Francis Willoughby regarding a land mortgage which she finds expensive in comparison with others he has offered to others. She agrees nonetheless, not because she wants his land, but because she desires the 'security of them that are to disburse this money'.

Sir Francis Willoughby writes to Bess (dowager countess of Shrewsbury) regarding the value of lands, claiming she has received erroneous reports from the surveyors. He hopes that she will still grant a mortgage.

Bess (dowager countess of Shrewsbury) writes to the earl and countess of Shrewsbury (her stepson and son-in-law, Gilbert, and her daughter, Mary), enquiring after their and the children's health and telling them of her own; advising them to come into the country where the air is better than in London. Also, she is assured that Master Winter has no right to 'the ground [he] pretendeth title to'.

Bess (dowager countess of Shrewsbury) writes to Walter Bagot, asking him to evict a widow Bagshaw who holds a farm unlawfully in Wetton and 'has used herself very disorderly and will yield to no reason'.